Azathioprine monotherapy withdrawal in inflammatory bowel diseases: A retrospective mono-centric study

Table 3 Incidence rates and unadjusted and adjusted hazard ratios of disease relapse in the overall population and different subgroups

Group or subgroup	Events	Rate per 10 person-yr (95%CI)	HR (95%CI)	Adjusted HR (95%CI)
Entire population	141	1.4 (1.2-1.7)
UC	64	1.4 (1.1-1.7)	1
CD	77	1.5 (1.2-1.8)	1.16 (0.8-1.6)
Males	85	1.7 (1.4-2.1)	1
Females	56	1.2 (0.9-1.5)	0.76 (0.5-1.1)
Age ≤ 35 yr	62	1.9 (1.4-2.4)	1
Age > 35 yr	79	1.2 (0.9-1.5)	0.69 (0.5-0.9)
Active patients	66	7.0 (5.5-8.9)	1	1
Patients in remission	21	0.7 (0.4-1.0)	0.17 (0.1-0.3)	0.17 (0.1-0.3)
Other groups	54	0.9 (0.7-1.2)	0.25 (0.2-0.4)	0.26 (0.1-0.4)

CD: Crohn's disease; CI: Confidence interval; HR: Hazard ratios; UC: Ulcerative colitis.