Non-invasive model for predicting high-risk esophageal varices based on liver and spleen stiffness

doi:10.3748/wjg.v29.i25.4072

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2023; 29(25): 4072-4084
Published online Jul 7, 2023. doi: 10.3748/wjg.v29.i25.4072

Table 4 Multivariate analysis of parameters of patients with high-risk esophageal varices and low-risk esophageal varices

Parameter	Patients with LEVs, n = 74	Patients with HEVs, n = 66	t/Z	P value
SSM, KPa	22.70 ± 6.00	19.06 ± 4.90	3.880	0.009
PLT, × 10⁹/L	108.55 ± 68.10	62.53 ± 29.00	5.096	0.606
LSM, KPa	14.90 ± 5.10	24.83 ± 4.30	-12.354	< 0.001
ALT, IU/L	37.50 (26.00, 49.50)	23.00 (16.00, 35.00)	-4.278	0.669
AST, IU/L	43.00 (31.75, 69.00)	34.50 (27.75, 45.25)	-2.796	0.125
	60.50 (28.00, 114.00)	33.00 (19.75, 58.75)	-3.609	0.790
SLD, mm	13.58 ± 3.10	15.10 ± 3.30	-2.806	0.952
PT, s	12.45 ± 2.20	13.34 ± 2.50	-2.284	0.883
INR	1.13 ± 0.20	1.21 ± 0.20	-2.175	0.777
PTA, %	82.15 ± 20.80	75.09 ± 16.10	2.228	0.920
PVD, mm	12.20 ± 1.90	13.64 ± 2.30	-4.024	0.220
CTLV, cm³	1031.88 ± 361.10	920.85 ± 241.50	2.111	0.892
CTSV, cm³	558.11 ± 338.70	808.25 ± 409.90	-3.951	0.713

P < 0.05 is considered statistically significant. HEVs: High-risk esophageal varices; LEVs: Low-risk esophageal varices; SSM: Spleen stiffness measurement; LSM: Liver stiffness measurement; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; SLD: Spleen long diameter; PT: Prothrombin time; INR: International prothrombin ratio; PTA: Prothrombin activity; PVD: Portal vein diameter; CTLV: Actual liver volume measured by computed tomography; CTSV: Actual spleen volume measured by computed tomography.

Citation: Yang LB, Gao X, Li H, Tantai XX, Chen FR, Dong L, Dang XS, Wei ZC, Liu CY, Wang Y. Non-invasive model for predicting high-risk esophageal varices based on liver and spleen stiffness. World J Gastroenterol 2023; 29(25): 4072-4084
URL: https://www.wjgnet.com/1007-9327/full/v29/i25/4072.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i25.4072