Non-invasive model for predicting high-risk esophageal varices based on liver and spleen stiffness

Table 3 Univariate analysis of parameters of patients with high-risk esophageal varices and low-risk esophageal varices

Parameter	Patients with LEVs, n = 74	Patients with HEVs, n = 66	t/Z	P value
SSM, KPa	22.70 ± 6.00	19.06 ± 4.90	3.880	< 0.001
PLT, × 109/L	108.55 ± 68.10	62.53 ± 29.00	5.096	< 0.001
LSM, KPa	14.90 ± 5.10	24.83 ± 4.30	-12.354	< 0.001
ALT, IU/L	37.50 (26.00, 49.50)	23.00 (16.00, 35.00)	-4.278	< 0.001
AST, IU/L	43.00 (31.75, 69.00)	34.50 (27.75, 45.25)	-2.796	0.005
ALP, IU/L	108.00 (81.25, 137.25)	93.50 (78.00, 128.75)	-1.012	0.311
GGT, IU/L	60.50 (28.00, 114.00)	33.00 (19.75, 58.75)	-3.609	< 0.001
SLD, mm	13.58 ± 3.10	15.10 ± 3.30	-2.806	0.006
TBIL, μmol/L	22.63 (16.01, 34.96)	27.80 (18.05, 39.65)	-0.960	0.337
ALB, g/dL	37.16 ± 8.30	36.02 ± 5.80	0.935	0.351
TCHO, mmol/L	3.57 ± 1.40	3.18 ± 0.90	1.981	0.050
PT, s	12.45 ± 2.20	13.34 ± 2.50	-2.284	0.024
INR	1.13 ± 0.20	1.21 ± 0.20	-2.175	0.031
PTA, %	82.15 ± 20.80	75.09 ± 16.10	2.228	0.028
PVD, mm	12.20 ± 1.90	13.64 ± 2.30	-4.024	< 0.001
CTLV, cm3	1031.88 ± 361.20	920.85 ± 241.50	2.111	0.037
CTSV, cm3	558.11 ± 338.70	808.25 ± 409.90	-3.951	< 0.001

P < 0.05 is considered statistically significant. HEVs: High-risk esophageal varices; LEVs: Low-risk esophageal varices; SSM: Spleen stiffness measurement; LSM: Liver stiffness measurement; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; GGT: Glutamine transferase; SLD: Spleen long diameter; TBIL: Total bilirubin; ALB: Albumin; TCHO: Total cholesterol; PT: Prothrombin time; INR: International prothrombin ratio; PTA: Prothrombin activity; PVD: Portal vein diameter; CTLV: Actual liver volume measured by computed tomography; CTSV: Actual spleen volume measured by computed tomography.