18β-glycyrrhetinic acid inhibits proliferation of gastric cancer cells through regulating the miR-345-5p/TGM2 signaling pathway

Figure 2 Effect of 18β-glycyrrhetinic acid on cell viability of GES-1, AGS and HGC-27 cells were detected by CCK-8 assay. A: Effect of 18β-glycyrrhetinic acid (18β-GRA) on cell viability of AGS cells; B: Effect of 18β-GRA on cell viability of HGC-27 cells; C: IC₅₀ value of AGS and HGC-27 cells were treated with 18β-GRA for 24, 48 and 72 h; D: Effect of low, medium and high doses of 18β-GRA on cell viability of AGS cells; E: Effect of low, medium and high doses of 18β-GRA on cell viability of HGC-27 cells; F: Effect of 18β-GRA on cell viability of GES-1 cells. All data are from three independent samples. The data is represented as the mean ± SD. ^aP < 0.05, ^bP < 0.01, ^cP < 0.001. 18β-GRA: 18β-glycyrrhetinic acid.