Lymphocyte-to-white blood cell ratio is associated with outcome in patients with hepatitis B virus-related acute-on-chronic liver failure

Table 3 Clinical characteristics between low and high lymphocyte-to-white blood cell ratio groups in hepatitis B virus-acute on chronic liver failure patients

	Low LWR level (n = 77)	High LWR level (n = 253)	P value
Age (yr)	52.99 ± 12.57	48.67 ± 12.19	0.007
Male, n (%)	59 (76.6)	218 (86.2)	0.046
Costs (dollars)	7625.18 (3899.37-12070.55)	10984.59 (6639.92-16693.10)	< 0.001
Ascites, n (%)			0.007
Mild	25 (32.5)	133 (52.6)
Medium	29 (37.7)	73 (28.9)
Severe	23 (29.9)	47 (18.6)
PLT (109/L)	86.00 (55.50-138.50)	110.00 (79.50-145.50)	0.039
PT (s)	23.20 (19.70-33.50)	22.40 (19.20-28.00)	0.016
INR	2.13 (1.76-3.11)	1.99 (1.73-2.54)	0.018
Hemoglobin (g/L)	109.00 (89.50-125.50)	125.00 (108.00-139.00)	< 0.001
Bilirubin (μmol/L)	331.52 ± 153.46	307.25 ± 129.82	0.170
Albumin (g/L)	30.10 (26.30-32.50)	31.80 (28.85-34.55)	< 0.001
Creatinine (μmol/L)	82.40 (58.40-126.10)	64.80 (56.85-77.95)	< 0.001
BUN (mmol/L)	7.00 (4.00-11.10)	3.70 (2.70-5.20)	< 0.001
Serum Na (mmol/L)	135.30 (131.50-139.05)	137.20 (133.90-139.10)	0.086
CTPs	12.00 (11.00-13.00)	11.00 (10.00-12.00)	< 0.001
MELDs	25.79 (22.52-30.91)	22.44 (19.55-26.13)	< 0.001
COSSHACLFIIs	8.11 (7.26-9.06)	6.94 (6.40-7.79)	< 0.001
28-d mortality, n (%)	46 (59.7)	89 (35.2)	< 0.001

PLT: Platelet; PT: Prothrombin time; INR: International normalized ratio; BUN: Blood urea nitrogen; LWR: Lymphocyte-to-white blood cell ratio; CTPs: Child-Turcotte-Pugh score; MELDs: Model for end-stage liver disease score; COSSHACLFIIs: Chinese group on the study of severe Hepatitis B-Acute-on-chronic liver failure II score.