Difference and clinical value of metabolites in plasma and feces of patients with alcohol-related liver cirrhosis

Figure 2 Subclass and distribution of common metabolites in the plasma and feces of patients with alcohol-related liver cirrhosis. A: Subclass of common metabolites in plasma and feces of patients with alcohol-related liver cirrhosis (ALC); B: Principal component analysis (PCA) of plasma metabolites in two groups; C: PCA of fecal metabolites in two groups. Green dots represent healthy control group, and red dots represented patients with ALC group. Abscissa PC 1 and ordinate PC 2 represent the scores of the first and second principal components respectively, each scatter point represented a sample, the closer the distribution of sample points, it indicates that the types and contents of metabolites in the samples are more similar. On the contrary, the farther the sample is, the greater the difference in its overall metabolic level. The sample is basically within the 95% confidence interval (Hotelling's T-squared ellipse). HC: Healthy control group; ALC: Alcohol-related liver cirrhosis group.