Study of the roles of caspase-3 and nuclear factor kappa B in myenteric neurons in a P2X7 receptor knockout mouse model of ulcerative colitis

Figure 10  Corrected total cell fluorescence of myenteric neurons. A: calretinin; B: P2X7 receptor; C: Cleaved caspase-3; D: Total caspase-3; E: Phospho-nuclear factor kappa B (NF-κB); F: Total NF-κB in the myenteric plexus of the distal colon in mice from the WT sham 24 h and 4 d, wild-type (WT) colitis 24 h and 4 d, knockout (KO) sham 24 h and 4 d, and KO colitis 24 h and 4 d groups. The data are presented as the arithmetic mean ± SE. ^aP < 0.05 vs sham groups; ^bP < 0.01 vs sham groups; ^cP < 0.001 vs sham groups; NS: Not significant. WT: Wild-type; KO: Knockout; NF-κB: Nuclear factor kappa B.