Study of the roles of caspase-3 and nuclear factor kappa B in myenteric neurons in a P2X7 receptor knockout mouse model of ulcerative colitis

Figure 1 The disease activity index of wild-type and knockout mice was determined beginning the day of ulcerative colitis induction or intrarectal injection of 35% ethanol. A: Changes in weight; B: Stool consistency; C: The presence of blood in the stool; D: Large intestine length was analyzed. DAI: Disease activity index; WT: Wild-type; KO: Knockout; TNBS: 2,4,6-trinitrobenzene sulfonic acid. The data are presented as the arithmetic mean ± SE. ^aP < 0.05 vs sham groups; NS: Not significant.