Observational Study
Copyright ©The Author(s) 2023.
World J Gastroenterol. Jun 14, 2023; 29(22): 3534-3547
Published online Jun 14, 2023. doi: 10.3748/wjg.v29.i22.3534
Table 1 Clinical characteristics of the study cohort
Characteristic
HC (n = 24)
ALC (n = 27)
P value
Age (yr)53 (48, 57.75) 51 (43, 60)0.527
BMI (kg/m2)22.92 (22.04, 24.09)24.22 (22.94, 24.94)0.101
Clinical lab index
WBC (109/L)5.82 (5.30, 6.76)4.57 (3.60, 6.62)0.023
NEU (%)56.20 (52.1, 60.55)56.60 (46.60, 67.90)0.678
RBC (1012/L)4.83 (4.52, 5.02)3.66 (2.90, 4.58)< 0.01
HGB (g/L)148.00 (144.00, 156.00)117.00 (100.00, 147.00)< 0.01
HCT (%)43.25(41.85, 46.8)33.60 (29.50, 42.50)< 0.01
MCV (fl)91.50 (88.35, 94.68)97.00 (92.2, 104.00)0.001
PLT (109/L)246 (223.25, 268.00)86.00 (46.00, 123.00)< 0.01
ALT (U/L)17.35 (12.75, 22.5)25.7 (15.1, 36.9)< 0.01
AST (U/L)19.7 (17.78, 21.73)36.7 (24.90, 74.20)< 0.01
TBil (μmol/L)13.95 (11.75, 15.20)47.3 (28.70, 115.70)< 0.01
ALB (g/L)46.48 (45.68, 47.68)34.27 (28.4, 39.5)< 0.01
A/G1.80 (1.63, 1.80)1.10 (0.80, 1.60)< 0.01
GGT (U/L)14.7 (10.28, 17.50)94.3 (25.00, 243.80)< 0.01
ALP (U/L)58.7 (53.05,70.05)97.9 (68.40, 137.50)< 0.01
CHE (U/L)8326.00 (7251.50, 9304.25)3547 (1700.00, 5735.00)< 0.01
TBA (μmol/L)1.90 (1.45, 2.50)66.1 (29.30, 174.20)< 0.01
T-CHO (mmol/L)4.40(3.72, 4.86)3.27 (2.54, 4.78)< 0.05
UREA (mmol/L)5.04 (4.12, 5.87)5.05 (4.29, 6.21)0.734
CREA (mmol/L)75.5 (72.18, 84.93)68.8 (60.5, 75.50)0.051
GLU (mmol/L) 5.27 (4.94, 5.76)5.24 (4.57, 6.08)0.977
PT(s)11.45 (11.20, 11.8)17.1 (12.10, 22.80)< 0.01
AFP (ng/mL)2.37 (1.97, 3.34)4.01 (2.70, 6.97)0.002
All clinical information in the table indicates data collected at the time closest to blood collection. Median and quartile values are provided as Median (upper quartile, lower quartile), unless otherwise noted as n (%). ALC: Alcohol-related liver cirrhosis; HC: Healthy control; CA: Cholic acid; TCA: Taurocholic acid; WBC: White blood cell; NEU: Neutrophilic granulocyte percentage; RBC: Red blood cell; HGB: Hemoglobin; HCT: Hematocrit; MCV: Mean corpuscular volume; PLT: Platelet; ALT: Alanine aminotransferase; AST: Aspartate transaminase; TBil: Total bilirubin; ALB: Albumin; A/G: Albumin/glubumin; GGT: γ-glutamyl transpeptidase; ALP: Alkaline phosphatase; CHE: Cholinesterase; TBA: Total bile acid; T-CHO: Total cholesterol; UREA: Urea nitrogen; CREA: Creatinine; PT: Prothrombin time; AFP: Alpha-fetoprotein.