Fibroblast growth factor 15, induced by elevated bile acids, mediates the improvement of hepatic glucose metabolism after sleeve gastrectomy

Figure 5 Sleeve gastrectomy regulated activities of the corresponding pathways of fibroblast growth factor 15. Western blotting for expression of extracellular signal regulated kinase (ERK), p-ERK, cAMP regulatory element-binding protein (CREB), p-CREB, glycogen synthase (GS), p-GS, and proliferator-activated receptor 𝛾 coactivator-1α (PGC-1α) in the liver of both SHAM and sleeve gastrectomy group at week 12 postoperation. PGC-1α: Proliferator-activated receptor 𝛾 coactivator-1α; ERK: Extracellular signal regulated kinase; CREB: cAMP regulatory element-binding protein; GS: Glycogen synthase; SG: Sleeve gastrectomy.