Fibroblast growth factor 15, induced by elevated bile acids, mediates the improvement of hepatic glucose metabolism after sleeve gastrectomy

doi:10.3748/wjg.v29.i21.3280

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Jun 7, 2023 (publication date) through Feb 2, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 7, 2023; 29(21): 3280-3291
Published online Jun 7, 2023. doi: 10.3748/wjg.v29.i21.3280

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Figure 3 Sleeve gastrectomy promoted fibroblast growth factor 15, fibroblast growth factor receptor 4 expression and hepatic glycogen synthesis. A and D: The result of immune-histochemistry staining for ileal fibroblast growth factor (FGF) 15; B and E: The result of Periodic Acid-Schiff staining for glycogen in hepatocytes; C and F: Immune-histochemistry staining of hepatic FGF receptor 4 in SHAM and sleeve gastrectomy group at week 12 postoperation. Scale bar: 100 μm. SG: Sleeve gastrectomy; FGF: Fibroblast growth factor; FGFR4: Fibroblast growth factor receptor 4.

Citation: Wei M, Cao WB, Zhao RD, Sun DP, Liang YZ, Huang YD, Cheng ZW, Ouyang J, Yang WS, Yu WB. Fibroblast growth factor 15, induced by elevated bile acids, mediates the improvement of hepatic glucose metabolism after sleeve gastrectomy. World J Gastroenterol 2023; 29(21): 3280-3291
URL: https://www.wjgnet.com/1007-9327/full/v29/i21/3280.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i21.3280