Retrospective Cohort Study
Copyright ©The Author(s) 2023.
World J Gastroenterol. Jun 7, 2023; 29(21): 3292-3301
Published online Jun 7, 2023. doi: 10.3748/wjg.v29.i21.3292
Table 1 Baseline demographics between manometric diagnoses, mean ± SD

Total (n = 181)
IEM (n = 31)
Normal motility (n = 130)
Other motility disorder (n = 20)
Follow-up (years)2.43 ± 2.452.85 ± 2.772.43 ± 2.411.76 ± 2.11
Male sex97 (53.6%)20 (64.5%)70 (53.8%)7 (35.0%)
BMI26.6 ± 4.3725.8 ± 3.8826.6 ± 4.5528.0 ± 3.66
Age at transplant (years)58.4 ± 10.257.9 ± 12.158.1 ± 10.261.6 ± 7.17
White race1166 (92.2%)24 (77.4%)123 (94.6%)20 (100%)
Pulmonary diagnosis
ILD99 (54.7%)19 (61.3%)69 (53.1%)11 (55.0%)
IPF74 (40.9%)14 (45.2%)51 (39.2%)9 (45.0%)
COPD57 (31.5%)7 (22.6%)43 (33.1%)7 (35.0%)
CF17 (9.39%)4 (12.9%)13 (10.0%)0 (0%)
Cardiac function2
LVEF (%)61.7 ± 5.7362.2 ± 5.7961.4 ± 5.4262.6 ± 7.55
PaP (mmHg)27.7 ± 10.328.6 ± 11.027.3 ± 10.329.2 ± 8.91
PCWP (mmHg)10.8 ± 4.969.06 ± 4.0111.2 ± 5.1511.5 ± 4.65
PVR (dynes/sec/cm-5)252 ± 194300 ± 238233 ± 175300 ± 217
Pulmonary function, baseline2
FVC1.93 ± 0.821.97 ± 0.921.94 ± 0.811.77 ± 0.78
FVC, %-pred50.1 ± 47.049.2 ± 18.450.1 ± 19.051.3 ± 24.4
FEV11.24 ± 0.681.39 ± 0.741.22 ± 0.681.15 ± 0.57
FEV1, %-pred40.5 ± 20.444.1 ± 21.139.4 ± 20.142.6 ± 21.6
FEV1/FVC0.66 ± 0.250.72 ± 0.220.64 ± 0.250.67 ± 0.26
Manometry results
Normal13001300
IEM313100
DES7007
Jackhammer7007
EGJOO6006
Reflux monitoring
Acid reflux69 (38.1%)13 (41.9%)50 (38.5%)6 (30.0%)
Nonacid reflux242 (26.6%)11 (39.3%)30 (26.8%)1 (5.56%)
Lungs transplanted
Unilateral43 (23.8%)6 (19.3%)34 (26.1%)3 (15.0%)
Bilateral138 (76.2%)25 (80.6%)96 (73.8%)17 (85.0%)
CMV mismatch53 (29.3%)7 (22.6%)42 (32.3%)4 (20.0%)
High-risk donor69 (38.1%)7 (22.6%)52 (40.0%)10 (50.0%)
Post-transplant PPI128 (70.7%)24 (77.4%)92 (70.8%)12 (60.0%)