Knowledge and attitudes towards the use of histological assessments in ulcerative colitis by gastroenterologists vs pathologists

Table 3 Impact of histological disease activity on treatment management in clinical scenarios, n (%)

Scenario	Never	Not often	Sometimes	Often	Always
If a patient is in clinical and endoscopic remission, but has histological activity, then I will escalate medical therapy	14 (18.2)	35 (45.5)	20 (26.0)	5 (6.5)	3 (3.9)
If a patient is in clinical and endoscopic remission, but has an elevated faecal calprotectin (> 100 μg/g) and histological activity, then I will escalate medical therapy	4 (5.2)	18 (23.4)	31 (40.3)	19 (24.7)	5 (6.5)
If a patient is in clinical, endoscopic and histological remission, (but prior colonoscopy showed Mayo 1 endoscopic disease), then I will de-escalate medical therapy	7 (9.1)	19 (24.7)	36 (46.8)	15 (19.5)	0 (0.0)
If a patient is in clinical remission, with their last 2 colonoscopies showing endoscopic and histological remission, then I will de-escalate medical therapy	2 (2.6)	2 (2.6)	31 (40.3)	38 (49.4)	4 (5.2)
If a patient with ulcerative colitis has other risk factors for colon cancer, then I will aim to achieve histological remission	0 (0.0)	7 (9.1)	14 (18.2)	27 (35.1)	29 (37.7)