Association of vitamin D and polymorphisms of its receptor with antiviral therapy in pregnant women with hepatitis B

Table 3 Factors associated with the targeted antiviral effects (hepatitis B viral deoxyribonucleic acid at delivery < 2 × 10⁵)

Variable	Univariate	P value	Multivariate	P value
Age (yr, continuous)	1.034 (0.85-1.26)	0.745		0.727
BMI (kg/m2, continuous)	1.18 (0.95-1.47)	0.146		0.071
25(OH) D3 (ng/mL, continuous)	1.16 (1.03-1.31)	0.014	1.23 (1.04-1.44)	0.026
VDR Cdx2 TT	0.2 (0.036-1.097)	0.064	0.09 (0.01-0.88)	0.039
Maternal GGT at delivery	0.94 (0.86-1.006)	0.075		0.05
Maternal VD at delivery (ng/mL, continuous)	1.1 (0.999-1.21)	0.053		0.385
Maternal alkaline phosphatase at delivery	0.98 (0.96-1.002)	0.081		0.64
Maternal cholesterol at delivery	0.47 (0.26-0.86)	0.015	0.39 (0.17-0.87)	0.021

BMI: Body mass index; 25(OH)D3: 25-hydroxyvitamin D3; VDR: Vitamin D receptor; GGT: Gamma-glutamyl transferase; VD: Vitamin D.