BanXiaXieXin decoction treating gastritis mice with drug-resistant Helicobacter pylori and its mechanism

Table 4 Minimum inhibitory concentration of Banxia Xiexin decoction aqueous extract against Helicobacter pylori (μg/mL)

Strain	Drug-resistanct strain	BXXXT aqueous extract	Berberine
26695	Sensitive	512	1024
G27	Sensitive	512	1024
NSH57	Sensitive	256	512
BHKS159	Resistant to levofloxacin, clarithromycin and metronidazole	512	1024
HPBS001	Resistant to levofloxacin, clarithromycin and metronidazole	512	1024
HPBS002	Resistant to metronidazole	512	1024
HPBS003	Resistant to clarithromycin	512	1024
HPBS004	Resistant to levofloxacin	512	1024
HPBS005	Resistant to levofloxacin and metronidazole	256	1024
HPBS006	Resistant to clarithromycin and metronidazole	256	1024
HPBS007	Resistant to clarithromycin	512	1024
HPBS010	Resistant to metronidazole, clarithromycin and levofloxacin	512	2048
HPBS011	Resistant to metronidazole and clarithromycin	512	1024
HPBS013	Resistant to metronidazole, clarithromycin and levofloxacin	512	1024
HPBS014	Resistant to metronidazole, clarithromycin, amoxicillin and levofloxacin	512	1024

BXXXT: Banxia Xiexin decoction. The minimum inhibitory concentrations of the drugs for sensitive and drug-resistant strains are amoxicillin ≥ 0.5 μg/mL, clarithromycin ≥ 1.0 μg/mL, levofloxacin ≥ 2.0 μg/mL, and metronidazole ≥ 8.0 μg/mL.