Predictive value of presepsin and acylcarnitines for severity and biliary drainage in acute cholangitis

Table 5 Variables associated with bloodstream infection multivariate logistic regression models

Variables	B	SE	Wald	df	OR	95%CI	P value
Presepsin (High vs low1)	1.243	0.524	5.617	1	3.466	1.240-9.689	0.018
Procalcitonin (High vs low2)	1.400	0.401	12.208	1	4.054	1.849-8.889	< 0.001
C2 (High vs low3)	1.313	0.464	7.998	1	3.716	1.496-9.229	0.005
C3 (High vs low4)	0.319	0.400	0.636	1	1.376	0.628-3.015	0.425
C6 (High vs low5)	-0.450	0.436	1.065	1	0.638	0.271-1.499	0.302
C12:1 OH (High vs low6)	1.284	0.410	9.829	1	3.611	1.618-8.058	0.002
Sex	0.282	0.356	0.628	1	1.326	0.660-2.667	0.428
Temperature (℃)	0.513	0.174	8.714	1	1.671	1.188-2.350	0.003
Severity grading	-0.071	0.285	0.062	1	0.932	0.533-1.628	0.804
SOFA score	-0.062	0.081	0.587	1	0.940	0.802-1.101	0.444

¹Presepsin (high vs low): > 1147.5 pg/mL vs ≤ 1147.5 pg/mL.

²Procalcitonin (high vs low): > 10.83 ng/mL vs ≤ 10.83 ng/mL.

³C2 (high vs low): > 14.59 μmol/L vs ≤ 14.59 μmol/L.

⁴C3 (high vs low): > 0.53 μmol/L vs ≤ 0.53 μmol/L.

⁵C6 (high vs low): > 0.12 μmol/L vs ≤ 0.12 μmol/L.

⁶C12:1 OH (high vs low): > 0.02 μmol/L vs ≤ 0.02 μmol/L.

C2: Acetyl-L-carnitine; C3: Propionyl-L-carnitine; C6: Hexanoyl-L-carnitine; C12:1 OH: Hydroxydodecenoyl-L-carnitine; SOFA: Sequential organ failure assessment; OR: Odds ratio; CI: Confidence interval.