Predictive value of presepsin and acylcarnitines for severity and biliary drainage in acute cholangitis

Table 3 Clinical variables and biomarkers associated with severity of acute cholangitis (multivariate logistic regression models)

	Mild vs moderate/severe		Mild/moderate vs severe
Variables	OR (95%CI)	P value	OR (95%CI)	P value
Presepsin (pg/mL)	1.001 (1.000-1.002)	< 0.001	1.000 (1.000-1.001)	< 0.001
Procalcitonin (ng/mL)	1.018 (0.995-1.041)	0.134	1.021 (1.008-1.035)	0.001
WBC (× 109/L)	1.149 (1.050-1.258)	0.003	0.990 (0.945-1.037)	0.676
CRP (mg/L)	1.001 (0.995-1.008)	0.642	1.003 (0.999-1.008)	0.104
TBIL(μmol/L)	1.008 (1.003-1.013)	0.003	0.999 (0.996-1.002)	0.504
Temperature (℃)	1.540 (1.046-2.267)	0.029	1.118 (0.859-1.456)	0.407
Age (yr)	1.051 (1.018-1.085)	0.002	1.000 (0.977-1.022)	0.973
C14:2 (μmol/L)	0.036 (0.002-0.663)	0.025	-	-
C5 (μmol/L)	-	-	11.490(2.213-59.656)	0.004

WBC: White blood cell; CRP: C-reactive protein; TBIL: Total bilirubin; C14:2: Tetradecadienyl-L-carnitine; C5: Valeryl-L-carnitine; OR: Odds ratio; CI: Confidence interval.