Ferroptosis inhibition attenuates inflammatory response in mice with acute hypertriglyceridemic pancreatitis

Figure 2 Effects of P-407 and caerulein on the pancreas revealed by proteome sequencing (n = 3). A: Principal component analysis; B: Heatmap showing relationships among different sample groups; C: Exhibition of changed protein numbers among the sample groups; D: Volcano plots showing proteins differentially expressed between sample groups; E: Biological process; F: Kyoto Encyclopedia of Genes and Genomes pathways enriched with proteins differentially expressed in pair-wise comparisons of ‘CAE group’ vs WT group’’ and ‘P-407 + CAE group’ vs CAE group’. CAE: Caerulein; WT: Wide type; PC: Principal component.