Repeat peroral endoscopic myotomy with simultaneous submucosal and muscle dissection as a salvage option for recurrent achalasia

Table 1 Demography and clinical profile of patients with recurrent achalasia after initial peroral endoscopic myotomy

	Total (n = 16)	Re-POEM (n = 9)	Re-POEM-SSMD (n = 7)	P value
Age, mean ± SD, yr	43.4 ± 16.3	43.0 ± 15.4	43.86 ± 18.7	0.916
Male, n (%)	9 (56.3)	4 (44.4)	5 (71.4)	0.008
Duration of dysphagia, median (range), mo	86.5 (16-420)	92 (16-147)	24 (16-420)	0.751
Time symptoms recurred after initial POEM, median (range), mo	15.5 (0-92)	12 (0-92)	7.5 (0-50)	0.414
Interval between initial POEM and Re-POEM, median (range), mo	45.5 (4-95)	64 (14-95)	9 (4-60)	0.013
Achalasia endoscopy type, n (%)
Ling I	2 (12.5)	2 (22.2)	0 (0)
Ling IIa	5 (31.3)	3 (33.3)	2 (28.6)
Ling IIb	1 (6.3)	0 (0)	1 (14.3)
Ling IIc	5 (31.3)	3 (33.3)	2 (28.6)
Ling IIIr	3 (18.8)	1 (11.1)	2 (28.6)

The values are expressed as mean ± SD or medians (range) for quantitative data, and n (%) for categorical data. SD: Standard deviation; POEM: Peroral endoscopic myotomy; Re-POEM: Repeat peroral endoscopic myotomy; Re-POEM-SSMD: Repeat peroral endoscopic myotomy with simultaneous submucosal and muscle dissection.