Effect and mechanism of reactive oxygen species-mediated NOD-like receptor family pyrin domain-containing 3 inflammasome activation in hepatic alveolar echinococcosis

Figure 2 Reactive oxygen species were highly produced in the hepatic alveolar echinococcosis marginal zone and were intimately associated with the activation of NOD-like receptor family pyrin domain-containing 3. A: Lesion growth in hepatic alveolar echinococcosis rats; B: Reactive oxygen species (ROS) production in the marginal zone and corresponding normal liver; C: Relative levels of ROS production; D: Relationship between ROS and NLRP3. C and D, n = 5 rats per group. ^dP < 0.0001. NLRP3: NOD-like receptor family pyrin domain-containing 3; ROS: Reactive oxygen species; FITC-A: Fluorescein isothiocyanate isomer I-A.