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Copyright ©The Author(s) 2023.
World J Gastroenterol. Apr 14, 2023; 29(14): 2127-2133
Published online Apr 14, 2023. doi: 10.3748/wjg.v29.i14.2127
Table 2 Proposed mechanisms of coronavirus disease 2019 cholangiopathy
No.
Proposed pathogenesis of COVID-19 cholangiopathy
1Cholangiocyte necrosis because of bile duct ischemia[24,25]
2Micro thrombosis of hepatic sinusoids and ischemic injury[6]
3Inflammation triggered due to cytokine release (cytokine release syndrome)
4Direct virus mediated damage[11]
5Drug induced liver injury in setting of severe COVID-19 infection (antibiotics, Remdesivir among others)
6Ketamine related cholangiopathy in setting of COVID-19[14]