Review
Copyright ©The Author(s) 2023.
World J Gastroenterol. Apr 14, 2023; 29(14): 2064-2077
Published online Apr 14, 2023. doi: 10.3748/wjg.v29.i14.2064
Table 2 Summary of the effective vaccines developed so far against coronavirus disease 2019
Sr. No.
Name of vaccine
FDA approval
Type of vaccine
Manufactured by
Efficacy
No. of doses
Safety profile
Ref.     
1NVX-CoV2373 vaccineDecember 20, 2021Recombinant SARS-CoV-2 nanoparticleNovavax92.6%2Safe till date[105]
2BNT162b2 vaccineFDA issued a EUA on December 11, 2020mRNA-basedBioNTech/Pfizer95%2Safe till date[106]
3mRNA-1273 vaccineFDA issued a EUA on December 18, 2020mRNA-1273 basedModerna94.1%2Safe till date[107]
4ChAdOx1 nCoV-19 vaccineNot yet received a EUA or approval from the FDARecombinant spike protein vaccineSerum institute of India, private limited70.4%2Vaccine-induced immune thrombotic thrombocytopenia[108]
5Ad26.COV2EUA by the FDA on February 27, 2021Recombinant vaccineJanssen-Cilag International, NV Belgium73.1%1Vaccine-induced immune thrombotic thrombocytopenia[109]
6CovaxinEUA for adultsWhole inactivated virus-basedBharat Biotech in collaboration with ICMR and NIV, India64%2Safe till date[110]
7Sputnik VEUA qualifiedHuman adenovirus vectorRussian direct investment fund97.2%2Safe till date[111]
8CoronaVacFDA issued under EUAInactivated virus alum-adjuvanted candidate vaccineSinovac biotech, China51% against symptomatic SARS-CoV-2 infection, 100% against severe COVID-192Safe till date[112]