Preoperative prediction of macrotrabecular-massive hepatocellular carcinoma through dynamic contrast-enhanced magnetic resonance imaging-based radiomics

Table 3 Results of univariate and multivariate logistic regression analyses

Variables	Univariate logistic regression		Multivariate logistic regression
	OR (95%CI)	P value	OR (95%CI)	P value
Clinical features
Age	0.930 (0.896, 0.964)	< 0.001	0.956 (0.918, 0.997)	0.034
AFP > 400 µg/L	13.248 (5.839, 30.058)	< 0.001	10.066 (4.304, 23.541)	< 0.001
PLT	1.006 (1.002, 1.011)	0.009	NA	NA
Radiological features
Tumour size > 5 cm	3.069 (1.487, 6.333)	0.002	3.316 (1.579, 6.962)	0.002
Tumour shape	2.342 (1.106, 4.961)	0.026	NA	NA
Intratumor necrosis	2.706 (1.326, 5.521)	0.006	NA	NA
Intratumor hemorrhage	2.466 (1.160, 5.244)	0.019	NA	NA
Tumour-to-liver ADC ratio	0.183 (0.035, 0.972)	0.046	0.156 (0.027, 0.894)	0.037
Radiomics
Rad-score	2.718 (1.809, 4.084)	< 0.001	2.923 (1.740, 4.911)	< 0.001

AFP: Alpha-fetoprotein; PLT: Platelet count; ADC: Apparent diffusion coefficient; OR: Odds ratio; CI: Confidence interval; NA: Not available.