Preoperative prediction of macrotrabecular-massive hepatocellular carcinoma through dynamic contrast-enhanced magnetic resonance imaging-based radiomics

Table 2 Radiological features of patients in the training and test sets

Radiological features	Training set (n = 162)			Test set (n = 70)			P value
	nMTM-HCC (n = 118)	MTM-HCC (n = 44)	P value	nMTM-HCC (n = 51)	MTM-HCC (n = 19)	P value
Liver cirrhosis (positive, %)	69 (58.5)	29 (65.9)	0.389	34 (66.7)	15 (78.9)	0.319	0.168
Tumour size > 5 cm, n (%)	29 (24.6)	22 (50.0)	0.002	12 (23.5)	10 (52.6)	0.020	0.994
Tumour shape (irregular, %)	25 (21.2)	17 (38.6)	0.024	17 (33.3)	7 (36.8)	0.783	0.195
Intratumor fat, n (%)	24 (20.3)	10 (22.7)	0.740	11 (21.6)	1 (5.3)	0.210	0.500
Intratumor necrosis, n (%)	34 (28.8)	23 (52.3)	0.005	13 (25.5)	8 (42.1)	0.177	0.443
Intratumor hemorrhage, n (%)	24 (20.3)	17 (38.6)	0.017	7 (13.7)	8 (42.1)	0.025	0.526
Enhancing capsule, n (%)	85 (72.0)	35 (79.5)	0.332	39 (76.5)	15 (78.9)	0.826	0.620
Tumour-to-liver ADC ratio	0.9 (0.2)	0.8 (0.3)	0.018	0.9 (0.1)	0.8 (0.2)	0.045	0.312

Data in parentheses are presented as median (interquartile range) or n (%). MTM-HCC: Macrotrabecular-massive hepatocellular carcinoma; nMTM-HCC: Non-macrotrabecular-massive hepatocellular carcinoma; ADC: Apparent diffusion coefficient.