Mitochondrial carnitine palmitoyltransferase-II dysfunction: A possible novel mechanism for nonalcoholic fatty liver disease in hepatocarcinogenesis

doi:10.3748/wjg.v29.i12.1765

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Mar 28, 2023 (publication date) through Nov 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 28, 2023; 29(12): 1765-1778
Published online Mar 28, 2023. doi: 10.3748/wjg.v29.i12.1765

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Figure 2 Carnitine palmitoyltransferase-II inactivity in hepatocarcinogenesis. Disorder of lipid metabolism may be related to the pathogenesis of nonalcoholic fatty liver disease with malignant transformation of hepatocytes. AFP: Alpha-fetoprotein; CoA: Coenzyme A; CPT2: Carnitine palmitoyl transferase 2; FAO: Fatty acid oxidation; HCC: Hepatocellular carcinoma; VEGF: Vascular endothelial-derived growth factor.

Citation: Yao M, Zhou P, Qin YY, Wang L, Yao DF. Mitochondrial carnitine palmitoyltransferase-II dysfunction: A possible novel mechanism for nonalcoholic fatty liver disease in hepatocarcinogenesis. World J Gastroenterol 2023; 29(12): 1765-1778
URL: https://www.wjgnet.com/1007-9327/full/v29/i12/1765.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i12.1765