Linked color imaging vs Lugol chromoendoscopy for esophageal squamous cell cancer and precancerous lesion screening: A noninferiority study

doi:10.3748/wjg.v29.i12.1899

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Mar 28, 2023 (publication date) through Jun 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 28, 2023; 29(12): 1899-1910
Published online Mar 28, 2023. doi: 10.3748/wjg.v29.i12.1899

Table 2 Esophageal neoplastic lesions (non-inflammation) detected using linked color imaging and Lugol chromoendoscopy

Parameter	LCI	LCE	P value
Sensitivity	83.7 (36/43)	90.7 (39/43)	0.520
Specificity	92.4 (462/500)	87.0 (435/500)	0.007¹
PPV	48.6 (36/74)	37.5 (39/104)	0.166
NPV	98.5 (462/469)	99.1 (435/439)	0.549

¹P < 0.01.

Data are presented as % (n/n total). LCE: Lugol chromoendoscopy; LCI: Linked color imaging; NPV: Negative predictive value; PPV: Positive predictive value.

Citation: Wang ZX, Li LS, Su S, Li JP, Zhang B, Wang NJ, Liu SZ, Wang SS, Zhang S, Bi YW, Gao F, Shao Q, Xu N, Shao BZ, Yao Y, Liu F, Linghu EQ, Chai NL. Linked color imaging vs Lugol chromoendoscopy for esophageal squamous cell cancer and precancerous lesion screening: A noninferiority study. World J Gastroenterol 2023; 29(12): 1899-1910
URL: https://www.wjgnet.com/1007-9327/full/v29/i12/1899.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i12.1899