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©The Author(s) 2023.
World J Gastroenterol. Mar 28, 2023; 29(12): 1875-1898
Published online Mar 28, 2023. doi: 10.3748/wjg.v29.i12.1875
Published online Mar 28, 2023. doi: 10.3748/wjg.v29.i12.1875
Table 5 Inhibitory effects of crude centipede peptides on HepG2 cells in different conditions
Concentration (mg/mL) | Suppression ratio (%) | ||||||||
Group 1 | Group 2 | Group 3 | Group 4 | Group 5 | Group 6 | Group 7 | Group 8 | Group 9 | |
0.039 | 12.510 | 6.880 | 12.070 | 5.394 | 3.389 | 3.213 | 0.570 | 1.641 | 7.094 |
0.078 | 22.270 | 11.240 | 13.060 | 16.430 | 12.890 | 4.709 | 2.280 | 4.540 | 9.883 |
0.156 | 45.770 | 36.430 | 45.680 | 52.290 | 18.610 | 16.620 | 26.110 | 11.540 | 33.170 |
0.3125 | 85.510 | 85.040 | 88.540 | 94.360 | 68.110 | 63.660 | 58.500 | 64.170 | 76.610 |
0.625 | 89.090 | 86.060 | 92.440 | 94.520 | 94.170 | 94.96 | 83.200 | 95.180 | 94.570 |
1.250 | 91.840 | 87.490 | 93.050 | 94.770 | 96.780 | 95.730 | 94.660 | 95.300 | 96.000 |
2.500 | 92.070 | 89.470 | 93.430 | 94.690 | 96.940 | 96.670 | 95.540 | 95.670 | 96.920 |
5.000 | 92.750 | 92.000 | 95.800 | 96.680 | 97.720 | 97.780 | 95.880 | 95.790 | 97.650 |
IC50 (mg/mL) | 0.457 | 0.310 | 0.480 | 0.360 | 0.584 | 0.681 | 0.812 | 0.757 | 0.278 |
Extract ratio (%) | 4.550 | 5.860 | 4.320 | 5.630 | 4.210 | 3.980 | 3.340 | 3.680 | 5.940 |
- Citation: Hu YX, Liu Z, Zhang Z, Deng Z, Huang Z, Feng T, Zhou QH, Mei S, Yi C, Zhou Q, Zeng PH, Pei G, Tian S, Tian XF. Antihepatoma peptide, scolopentide, derived from the centipede scolopendra subspinipes mutilans. World J Gastroenterol 2023; 29(12): 1875-1898
- URL: https://www.wjgnet.com/1007-9327/full/v29/i12/1875.htm
- DOI: https://dx.doi.org/10.3748/wjg.v29.i12.1875