Systemic treatment for metastatic colorectal cancer

doi:10.3748/wjg.v29.i10.1569

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Mar 14, 2023 (publication date) through Nov 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 14, 2023; 29(10): 1569-1588
Published online Mar 14, 2023. doi: 10.3748/wjg.v29.i10.1569

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Figure 2 Targeted therapy for metastatic colorectal cancer. AKT: Ak strain transforming; D: Down regulation pathway; EGFR: Epidermal growth factor receptor; HER2: Human epidermal growth factor receptor 2; IRS1/2: Insulin receptor substrates 1 or 2; MAPK: Mitogen activated protein kinase; mTOR: Mammalian target of rapamycin; MEK: Mitogen-activated protein kinase kinase; NTRK: Neurotrophic tyrosine receptor kinase; PTEN: Phosphatase and tensin homolog; PI3K: Phosphoinositide 3-kinases; RAF: Rapidly accelerated fibrosarcoma; RAS: Rat sarcoma virus; SOS: Son of sevenless.

Citation: Leowattana W, Leowattana P, Leowattana T. Systemic treatment for metastatic colorectal cancer. World J Gastroenterol 2023; 29(10): 1569-1588
URL: https://www.wjgnet.com/1007-9327/full/v29/i10/1569.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i10.1569