Systemic treatment for metastatic colorectal cancer

doi:10.3748/wjg.v29.i10.1569

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Mar 14, 2023 (publication date) through Nov 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 14, 2023; 29(10): 1569-1588
Published online Mar 14, 2023. doi: 10.3748/wjg.v29.i10.1569

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Figure 1 Three molecular pathways can lead to colorectal cancer. For colorectal carcinogenesis, three molecular pathways have been proposed: the chromosomal instable or classic pathway, the microsatellite instability pathway, and the serrated pathway. APC: Adenomatous polyposis coli; BRAF: Protein kinase B-Raf; CIMP: CpG island methylator phenotype; KRAS: Kristin rat sarcoma virus.

Citation: Leowattana W, Leowattana P, Leowattana T. Systemic treatment for metastatic colorectal cancer. World J Gastroenterol 2023; 29(10): 1569-1588
URL: https://www.wjgnet.com/1007-9327/full/v29/i10/1569.htm
DOI: https://dx.doi.org/10.3748/wjg.v29.i10.1569