In vivo recognition of bioactive substances of Polygonum multiflorum for protecting mitochondria against metabolic dysfunction-associated fatty liver disease

Table 3 Effects of the Polygonum multiflorum-derived monomer group in liver mitochondria extract on body weight, food intake, and organ indices of rats

	NC	MOD	RES	LMG	HMG
Initial body weight (g)	20.03 ± 0.54	20.38 ± 0.32	20.40 ± 0.59	19.83 ± 0.92	20.33 ± 1.00
Final body weight (g)	22.90 ± 0.56b	25.68 ± 1.12	24.22 ± 1.29	25.20 ± 1.74	24.37 ± 1.50
Body weight gain (g)	2.87 ± 0.02	5.30 ± 0.79	3.82 ± 0.70	5.37 ± 0.82	4.03 ± 0.50
Food intake (g)	2274.20	2268.50	2655.80	2473.30	2290.60
Liver index (%)	3.52 ± 0.05c	4.24 ± 0.10	3.17 ± 0.11c	3.16 ± 0.11c	3.50 ± 0.21c
Kidney index (%)	1.00 ± 0.57c	1.20 ± 0.05	1.11 ± 0.08	1.15 ± 0.08	1.15 ± 0.08
Spleen index (%)	0.21 ± 0.03	0.31 ± 0.06	0.31 ± 0.04	0.30 ± 0.06	0.48 ± 0.22a

^aP < 0.05 vs model group.

^bP < 0.01 vs model group.

^cP < 0.001 vs model group.

Values represent the mean ± SD from six animals. HMG: High-dose Polygonum multiflorum-derived monomer group; LMG: Low-dose Polygonum multiflorum-derived monomer group; MOD: Model; NC: Normal control; RES: Resveratrol.