Observational Study
Copyright ©The Author(s) 2022.
World J Gastroenterol. Mar 7, 2022; 28(9): 961-972
Published online Mar 7, 2022. doi: 10.3748/wjg.v28.i9.961
Table 2 Characteristics of perianal fistulas at each visit according to the presence of clinical remission

Clinical remission, n (%) unless otherwise specified
No, n = 34
Yes, n = 22
PAF duration (Time from fistula diagnosis to date of visit) in mo, Med [IQR]12 [8-23.5]53.5 [32.75-81.75]
Drainage duration (Time from seton setting down to date of visit) in mo, Med [IQR]9 [4.75-17]8 [4-19]
Combination therapy (with methotrexate or thiopurine)23 (68%)7 (32%)
Optimization19 (56%)14 (64%)
Serum concentrations of ADA (μg/mL), Med [IQR]10.7 [2.4-14.7]14.1 [9.8-16]
C reactive protein (mg/L), Med [IQR]2.7 [0.07-15.25]0.9 [0-1.8]
Serum albumin (g/L), Med [IQR]42 [38.25-47.3]43 [41.85-44.25]
Length of treatment by ADA in mo, Med [IQR]12 [6-34.75]37.5 [23.75-46.75]

  • Citation: Sirmai L, Pelletier AL, Gault N, Zallot C, Bouguen G, Bouchard D, Roland Nicaise P, Peyneau M, Sironneau S, Bittencourt MDC, Petitcollin A, Fernandez P, Roblin X, Siproudhis L, Abramowitz L. Relationship between clinical remission of perianal fistulas in Crohn’s disease and serum adalimumab concentrations: A multi-center cross-sectional study. World J Gastroenterol 2022; 28(9): 961-972
  • URL: https://www.wjgnet.com/1007-9327/full/v28/i9/961.htm
  • DOI: https://dx.doi.org/10.3748/wjg.v28.i9.961