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©The Author(s) 2022.
World J Gastroenterol. Mar 7, 2022; 28(9): 933-947
Published online Mar 7, 2022. doi: 10.3748/wjg.v28.i9.933
Published online Mar 7, 2022. doi: 10.3748/wjg.v28.i9.933
Table 3 Clinicopathological features by sex and histologic type
| Characteristics | Intestinal type | Diffuse type | ||||
| Female (n = 447) | Male (n = 1396) | P value | Female (n = 494) | Male (n = 520) | P value | |
| Age (yr, mean ± SD) | 65.72 ± 10.71 | 64.06 ± 10.34 | 0.792 | 53.60 ± 13.06 | 55.82 ± 12.48 | 0.229 |
| Drinking history, n (%) | ||||||
| No | 385 (86.1) | 619 (44.3) | < 0.001a | 374 (75.7) | 183 (35.2) | < 0.001a |
| Yes | 62 (13.9) | 777 (55.7) | 120 (24.3) | 337 (64.8) | ||
| Smoking history, n (%) | ||||||
| No | 420 (94.0) | 530 (38.0) | < 0.001a | 447 (90.5) | 175 (33.7) | < 0.001a |
| Yes | 27 (6.0) | 866 (62.0) | 47 (9.5) | 345 (66.3) | ||
| Family history, n (%) | ||||||
| No | 348 (77.9) | 1138 (81.5) | 0.088 | 419 (84.8) | 447 (86.0) | 0.606 |
| Yes | 99 (22.1) | 258 (18.5) | 75 (15.2) | 73 (14.0) | ||
| Tumor location, n (%) | ||||||
| Upper | 12 (2.7) | 44 (3.2) | 0.053 | 7 (1.4) | 10 (1.9) | < 0.001a |
| Middle | 139 (31.1) | 517 (37.0) | 334 (67.6) | 284 (54.6) | ||
| Lower | 296 (66.2) | 835 (59.8) | 153 (31.0) | 226 (43.5) | ||
| Atrophic gastritis, n (%) | ||||||
| No | 320 (71.6) | 951 (68.1) | 0.168 | 400 (81.0) | 389 (74.8) | 0.018a |
| Yes | 127 (28.4) | 445 (31.9) | 94 (19.0) | 131 (25.2) | ||
| Intestinal metaplasia, n (%) | ||||||
| No | 229 (51.2) | 751 (53.8) | 0.344 | 303 (61.3) | 306 (58.8) | 0.418 |
| Yes | 218 (48.8) | 645 (46.2) | 191 (38.7) | 214 (41.2) | ||
| T stage, n (%) | ||||||
| T1 | 355 (79.4) | 1087 (77.9) | 0.529 | 314 (63.6) | 305 (58.6) | 0.445 |
| T2 | 40 (9.0) | 138 (9.9) | 57 (11.5) | 66 (12.7) | ||
| T3 | 40 (9.0) | 145 (10.4) | 99 (20.0) | 118 (22.7) | ||
| T4 | 12 (2.6) | 26 (1.8) | 24 (4.9) | 31 (6.0) | ||
| N stage, n (%) | ||||||
| N0 | 356 (79.6) | 1140 (81.7) | 0.745 | 319 (64.6) | 335 (64.4) | 0.055 |
| N1 | 56 (12.5) | 149 (10.7) | 97 (19.6) | 85 (16.4) | ||
| N2 | 20 (4.5) | 62 (4.4) | 42 (8.5) | 38 (7.3) | ||
| N3 | 15 (3.4) | 45 (3.2) | 36 (7.3) | 62 (11.9) | ||
| Stage, n (%) | ||||||
| I | 375 (83.9) | 1171 (83.9) | 0.49 | 342 (69.2) | 347 (66.7) | 0.152 |
| II | 47 (10.5) | 142 (10.2) | 96 (19.5) | 89 (17.1) | ||
| III | 23 (5.1) | 65 (4.6) | 43 (8.7) | 66 (12.7) | ||
| IV | 2 (0.5) | 18 (1.3) | 13 (2.6) | 18 (3.5) | ||
| Cancer type, n (%) | ||||||
| EGC | 355 (79.4) | 1086 (77.8) | 0.469 | 314 (63.6) | 305 (58.7) | 0.109 |
| AGC | 92 (20.6) | 310 (22.2) | 180 (36.4) | 215 (41.3) | ||
| P53, n (%) | ||||||
| Negative | 293 (65.5) | 770 (55.2) | < 0.001a | 385 (77.9) | 393 (75.6) | 0.374 |
| Positive | 154 (34.5) | 626 (44.8) | 109 (22.1) | 127 (24.4) | ||
- Citation: Choi Y, Kim N, Kim KW, Jo HH, Park J, Yoon H, Shin CM, Park YS, Lee DH, Oh HJ, Lee HS, Park YS, Ahn SH, Suh YS, Park DJ, Kim HH, Kim JW, Kim JW, Lee KW, Chang W, Park JH, Lee YJ, Lee KH, Kim YH. Sex-based differences in histology, staging, and prognosis among 2983 gastric cancer surgery patients. World J Gastroenterol 2022; 28(9): 933-947
- URL: https://www.wjgnet.com/1007-9327/full/v28/i9/933.htm
- DOI: https://dx.doi.org/10.3748/wjg.v28.i9.933