Retrospective Study
Copyright ©The Author(s) 2022.
World J Gastroenterol. Feb 28, 2022; 28(8): 840-852
Published online Feb 28, 2022. doi: 10.3748/wjg.v28.i8.840
Table 1 Baseline characteristics of the study population
VariablesBefore matching
After matching
ESD (n = 123)
Surgery (n = 562)
P value
ESD (n = 119)
Surgery (n = 119)
P value
Age, yr, mean SD55.3 12.453.0 11.8< 0.00156.6 11.955.6 11.90.546
Male, n (%)68 (55.3)282 (50.2)0.30567 (56.3)57 (47.9)0.194
Comorbidity, n (%)
Hypertension44 (35.8)143 (25.4)0.02041 (34.5)40 (33.6)0.891
Diabetes21 (17.1)65 (11.6)0.09519 (16.0)15 (12.6)0.459
Cerebrovascular disease8 (6.5)18 (3.2)0.1137 (5.9)2 (1.7)0.171
Respiratory disease7 (5.7)29 (5.2)0.8116 (5.0)6 (5.0)-
Liver disease3 (2.4)26 (4.6)0.2753 (2.5)3 (2.5)-
Renal disease2 (1.6)4 (0.7)0.2941 (0.8)1 (0.8)-
ASA physical status1, n (%)0.0220.254
1101 (82.1)503 (89.5)100 (84.0)106 (89.1)
222 (17.9)59 (10.5)19 (16.0)13 (10.9)
Tumor location, n (%)< 0.0010.822
Upper third8 (6.5)55 (9.8)8 (6.7)6 (5.0)
Middle third97 (78.9)321 (57.1)93 (78.2)93 (78.2)
Lower third18 (14.6)186 (33.1)18 (15.1)20 (16.8)
Lesion size, mm, n (%)0.4300.418
1030 (24.4)105 (18.7)28 (23.5)19 (16.0)
10-2050 (40.7)224 (39.9)50 (42.0)49 (41.2)
20-3024 (19.5)133 (23.7)22 (18.5)28 (23.5)
> 3019 (15.4)100 (17.8)19 (16.0)23 (19.3)
Gross morphology type1, n (%)0.3150.760
Elevated33 (26.8)127 (22.6)29 (24.4)27 (22.7)
Flat or depressed90 (73.2)435 (77.4)90 (75.6)92 (77.3)
Helicobacter pylori infection, n (%)64 (51.2)316 (56.2)0.39761 (51.3)60 (50.4)0.897
ESD indication, n (%)0.1830.183
Within expanded indication80 (65.0)329 (58.5)78 (65.5)68 (57.1)
Beyond expanded indication43 (35.0)233 (41.5)41 (34.5)51 (42.9)
Histology appearance, n (%)< 0.0010.794
Poorly differentiated carcinoma56 (45.5)151 (26.9)52 (43.7)54 (45.4)
Signet ring cell carcinoma67 (54.5)411 (73.1)67 (56.3)65 (54.6)