Mixed neuroendocrine–nonneuroendocrine neoplasms of the gastrointestinal system: An update

doi:10.3748/wjg.v28.i8.794

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Feb 28, 2022 (publication date) through Feb 18, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 28, 2022; 28(8): 794-810
Published online Feb 28, 2022. doi: 10.3748/wjg.v28.i8.794

Table 3 Summary of the therapy protocols applied to localized mixed neuroendocrine-nonneuroendocrine neoplasms

Surgery	Complete resection is possible			Complete resection is not possible
MiNEN grade	High	Intermediate	Low	High	Intermediate	Low
Chemotherapy	PDNEC-like	ADC-like	NR	PDNEC-like	ADC- like	NET-like

MiNEN: Mixed neuroendocrine-nonneuroendocrine neoplasms; ADC: Adenocarcinoma; PDNEC: Poorly differentiated neuroendocrine carcinoma; NET: Neuroendocrine tumor.

Citation: Elpek GO. Mixed neuroendocrine–nonneuroendocrine neoplasms of the gastrointestinal system: An update. World J Gastroenterol 2022; 28(8): 794-810
URL: https://www.wjgnet.com/1007-9327/full/v28/i8/794.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i8.794