Clinical implications of diabetes in chronic liver disease: Diagnosis, outcomes and management, current and future perspectives

Table 1 Clinical differences between hepatogenous diabetes and type 2 diabetes mellitus

Variables	Hepatogenous diabetes	Type 2 diabetes mellitus
Onset	After cirrhosis onset	Before cirrhosis onset
Clinical presentation	Normal FPG and HbA1c; Abnormal OGTT	Increased FPG and HbA1c
Metabolic risk Factors	Less frequent	More frequent
Vascular complications	Less frequent	More frequent
Liver complication	More frequent	Less frequent
Effect of OLT	Reversal or improvement	Non modification
Mortality	More than non-diabetics	More than non-diabetics

FPG: Fasting plasma glucose; OGTT: Oral glucose tolerance test; OLT: Orthotopic liver transplantation; HbA1c: Glycated hemoglobin.