Atrophic gastritis and gastric cancer tissue miRNome analysis reveals hsa-miR-129-1 and hsa-miR-196a as potential early diagnostic biomarkers

Figure 1 Results of microRNA differential expression analysis. A: Differentially expressed gastric tissue microRNAs among different conditions. P-adjusted < 0.05 and |log2 fold change| > 1; B: Multidimensional scaling plot based on normalized data showing a clustering corresponding to control, atrophic gastritis, gastric cancerous and adjacent tissues. The density plots show distributions of the first and second dimensions. CON: Control; AG: Atrophic gastritis; GC: Gastric cancerous; GCaj: Gastric adjacent tissue; MDS: Multidimensional scaling.