Curative resection with endoscopic submucosal dissection of early gastric cancer in Helicobacter pylori-negative Ménétrier’s disease: A case report

Figure 4 Histological findings. A: The protruding lesion exhibits proliferation of atypical glands with irregular tubular structures (HE; × 20); B: High magnification shows proliferation of atypical cells and enlarged nuclei (irregular or oval-shaped) in the irregular tubular structure (HE; × 20); C: Scattered positive image (in nuclei) in the region (p53; × 20); D: Foveolar hyperplasia and atrophy of the proper gastric glands in non-cancerous area, consistent with Ménétrier’s disease (HE; × 20).