Nanotechnology for colorectal cancer detection and treatment

Figure 2 Advantages of nanoparticles in cancer drug delivery. Nanoparticles along with extracellular vesicles or viruses improve the clinical efficacy of various therapeutic molecules (nucleic acids, antibodies, drugs, radionuclides) with efficient delivery of these molecules to the tumor with minimal off-targeting. Nanoparticles enhance the transport of these molecules by increasing their solubility, bioavailability and half-life in the bloodstream. The tumor delivery of therapeutic molecules is also enhanced by nanoparticles, leading to their accumulation and thus potentiating the use of various combination therapies for colorectal cancer. Citation: Briolay T, Petithomme T, Fouet M, Nguyen-Pham N, Blanquart C, Boisgerault N. Delivery of cancer therapies by synthetic and bio-inspired nanovectors. Mol Cancer 2021; 20: 55. Copyright© The Author(s) 2021. Published by Springer Nature. The authors have obtained the permission for figure using from the Springer Nature Publishing Group (Supplementary material).