Upper gastrointestinal endoscopic findings in celiac disease at diagnosis: A multicenter international retrospective study

Table 3 Demography and endoscopic findings in celiac disease patients and non-celiac disease controls of the Buenos Aires cohort

Demographic data and upper GI endoscopic findings	CeD population	Non-CeD population	≤ 50 yr non-CeD	51-60 yr non-CeD	≥ 61 yr non-CeD
Patients	97 (12.6)	674 (87.4)	435 (64.5)	135 (20.0)	104 (15.4)
Age in yr	35 (27-44)	45 (33-55)a	37 (29-44)	55 (53-58)	68 (63-72)
Female sex	88 (90.7)	472 (70.0)a	312 (71.7)	92 (68.1)	68 (65.4)
Patients with positive serology	97 (100)	9 (1.3)a	6 (1.3)	3 (2.2)	0
Patients with at least one significant endoscopic abnormalities	8 (8.2)	196 (29.1)b	121 (27.8)	48 (35.6)	27 (26.0)
Reflux esophagitis with erosions	1 (1.0)	21 (3.1)	11 (2.5)	2 (1.5)	5 (4.8)
Esophageal ulcers	0	0	0	0	0
Esophageal cancer	0	0	0	0	0
Suspicion of metaplasia	0	7 (1.0)	5 (1.1)	2 (1.5)	0
Biopsy confirmed Barrett's esophagus	0	2 (0.3)	2 (0.5)	0	0
Gastric erosions	7 (7.22)	165 (24.5)a	103 (23.7)	43 (31.8)	19 (18.3)
Gastric ulcers	0 (0)	11 (1.6)	4(0.9)	2 (1.5)	5 (4.8)
Gastric cancer	0	2 (0.3)	0	1 (0.7)	1 (1.0)
Duodenal erosions	0	10 (1.5)	6 (1.4)	2 (1.5)	2 (1.9)
Duodenal ulcers	1 (1.0)	5 (0.7)	2 (0.5)	2 (1.5)	1 (1.0)
Duodenal cancer	0	1 (0.1)	1 (0.2)	0	0

^aP < 0.01.

^bP < 0.001.

Data are presented as n (%) or median and 25% interquartile range. Controls were grouped according to age at endoscopy. Comparisons between celiac disease patients vs non-celiac disease controls.

CeD: Celiac disease; GI: Gastrointestinal; IQR: Interquartile range.