Differential analysis of intestinal microbiota and metabolites in mice with dextran sulfate sodium-induced colitis

Table 2 Scoring criteria for histological lesions in the colon

Content	Score
	0	1	2	3	4
Goblet cells	No loss	Mild loss	Moderate loss	Severe loss
Mucosal thickness	No change	Mild thickening	Moderate thickening	Severe thickening
Inflammatory cells	No infiltration	Mild increase	Moderate increase	Severe increase
Submucosal inflammatory cell infiltration	No infiltration		Mild increase	Moderate increase	Severe increase
Degree of disruption of mucosal structures	No damage			Mild destruction	Moderate destruction
Percentage of epithelial cell ulcer area	No ulcers	0%-25%	25%-50%	50%-75%	75%-100%
Number of crypt abscesses	No	1–3	4–6	7–9	> 10