Epidemiology of liver cirrhosis and associated complications: Current knowledge and future directions

Table 4 Latest global epidemiological features of cirrhosis

Ref.	Epidemiological figures	Latest research	Type or etiology of cirrhosis	Reported data
Prevalence
[6]	Age-standardized prevalence	GBD 2017	Cirrhosis	Compensated cirrhosis: 1395.0 (1323.5-1470.5); decompensated cirrhosis: 132.5 (128.6-136.2) per 100000
[6]	Age-standardized prevalence	GBD 2017	HBV-related cirrhosis	Compensated cirrhosis: 451.9 (420.0-485.9); decompensated cirrhosis: 36.6 (34.7-38.4)
[6]	Age-standardized prevalence	GBD 2017	HCV-related cirrhosis	Compensated cirrhosis: 341.1 (314.1-368.7); decompensated cirrhosis: 32.5 (30.6-34.5)
[6]	Age-standardized prevalence	GBD 2017	Alcohol-related cirrhosis	Compensated cirrhosis: 288.1 (267.5-311.3); decompensated cirrhosis: 30.0 (28.2-31.8)
[6]	Age-standardized prevalence	GBD 2017	NASH-related cirrhosis	Compensated cirrhosis: 115.5 (105.0-126.5); decompensated cirrhosis: 11.3 (10.4-12.1)
Incidence
[24]	Age-standardized incidence	GBD 2017	NASH-related cirrhosis	4.81 (4.38-5.28)
[26]	Age-standardized incidence	GBD 2019	HBV-related cirrhosis	4.91 (3.50-6.50)
[26]	Age-standardized incidence	GBD 2019	HCV-related cirrhosis	6.7 (5.0-8.6)
Mortality
[26]	Age-standardized Mortality	GBD 2019	HBV-related cirrhosis	4.03 (3.39-4.76)
[26]	Age-standardized Mortality	GBD 2019	HCV-related cirrhosis	4.82 (4.09-5.57)
[25]	Age-standardized mortality	GBD 2017	NASH-related cirrhosis	1.5 (1.3-1.6)
Public health burden
[52]	DALYs	GBD 2019	HBV-related cirrhosis	129.8 (95%CI 108.3-153.0)
[52]	DALYs	GBD 2019	HCV-related cirrhosis	146.2 (124.4-169.8)

GBD: Global burden of diseases, injuries, and risk factors study; HBV: Hepatitis B virus; HCV: Hepatitis C virus; UI: Uncertainty interval; CI: Confidence interval; NASH: Nonalcoholic steatohepatitis; DALYs: Disability-adjusted life-years.