Curcumin alleviates experimental colitis via a potential mechanism involving memory B cells and Bcl-6-Syk-BLNK signaling

Figure 5 Curcumin regulates differentiation of memory B cells in DSS-induced ulcerative colitis mice. A: Representative flow cytometry profile of CD19⁺ CD27⁺ IgG⁺ cells in peripheral blood; B: Bar chart of CD19⁺ CD27⁺ IgG⁺ cells; C: Representative flow cytometry profile of CD19⁺ CD27⁺ IgM⁺ cells in peripheral blood; D: Bar chart of CD19⁺ CD27⁺ IgM⁺ cells; E: Representative flow cytometry profile of CD19⁺ CD27⁺ IgA⁺ cells in peripheral blood; F: Bar chart of CD19⁺ CD27⁺ IgA⁺ cells. Data are presented as the mean ± SE (n = 8-10). ^aP < 0.05, ^bP < 0.01 vs Control group; ^cP < 0.05, ^dP < 0.01 vs DSS group.