Curcumin alleviates experimental colitis via a potential mechanism involving memory B cells and Bcl-6-Syk-BLNK signaling

Figure 2 Therapeutic evaluation of curcumin on DSS-induced experimental colitis. A: Body weight of mice from days 0-22; B: Weight change of rate in mice from days 1-22; C: OB scores of mice in the four groups from days 1-22; D: DAI scores of mice in the four groups from days 1-22; E: Gross changes in colonic length; F: Colonic length of mice on day 22 in the four groups; G: Colonic weight; H: Body weight; I: Colonic weight index; J: Colonic weight/colonic length; K: Spleen weight; L: Spleen weight/body weight; M: Histological appearance of colons from individual groups of mice (hematoxylin and eosin staining, magnification 50 ×, scale bar = 100 μm); N: Pathological injury score. Data are presented as the mean ± SE (n = 8-10). ^aP < 0.05, ^bP < 0.01 vs Control group; ^cP < 0.05, ^dP < 0.01 vs DSS group.