Heterogeneity of immune control in chronic hepatitis B virus infection: Clinical implications on immunity with interferon-α treatment and retreatment

doi:10.3748/wjg.v28.i40.5784

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 28, Issue 40

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (3727)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-4) series, Tables (1-4) series.

Item

Count

PDF

186

WORD

HTML

2377

Figures (1-4)

163

Tables (1-4)

253

Sum=3016

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

251

Download

460

Sum=711

Oct 28, 2022 (publication date) through Jul 22, 2024

Times Cited of This Article

Times Cited (1)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Minireviews

World J Gastroenterol. Oct 28, 2022; 28(40): 5784-5800
Published online Oct 28, 2022. doi: 10.3748/wjg.v28.i40.5784

Table 3 Host genetic variants associated with interferon-α therapy[43,44,74-78,91]

Gene ontology	Gene	Genetic determinants (SNP/Hap/CNVs)
HLA	HLA-DP	rs3077, rs9277535
	HLA-DQA1-DQB1-DRB1	0302-0303-*09
	HLA-DQB1	*0303
	HLA-DRB1	*08
	HLA-A, B, C	1101-4601-*0102
Cytokines	IL-28B	A-C¹,rs8099917, rs12979860, rs12980275
Others	CYP24A1	rs2248359
	CYP27B1	rs10877012, rs4646536
	G3BP2	rs3821977
	OAS	G-T-G-A², C-C-T-A³, C-C-C-A⁴, A-C-T-A⁵
	OAS3	rs2072136
	PRELID2	rs371991
	STAT4	rs7574865
	TRAPPC9	rs78900671
	VDBP	rs7041
	VDR	rs1544410, rs731236, rs11568820, rs10735810

Haplotypes:

¹A-C, rs12980275-rs12979860.

²G-T-G-A, rs3177979-rs1293747-rs4767043-rs10849829.

³C-C-T-A, rs2285934-rs2072138-rs2072136-rs10849829.

⁴C-C-C-A, rs2285934- rs2072138-rs2072136-rs10849829.

⁵A-C-T-A, rs2285934-rs2072138-rs2072136-rs10849829.

SNPs/Hap/CNVs: Single nucleotide polymorphisms/Haplotype/Copy number variations; HLA: Human leukocyte antigen.

Citation: Yin GQ, Chen KP, Gu XC. Heterogeneity of immune control in chronic hepatitis B virus infection: Clinical implications on immunity with interferon-α treatment and retreatment. World J Gastroenterol 2022; 28(40): 5784-5800
URL: https://www.wjgnet.com/1007-9327/full/v28/i40/5784.htm
DOI: https://dx.doi.org/10.3748/wjg.v28.i40.5784