Fibrinogen-like protein 2 deficiency inhibits virus-induced fulminant hepatitis through abrogating inflammatory macrophage activation

Figure 7 Fibrinogen-like protein 2 deficiency resulted in low expression of major histocompatibility complex II and impaired phagocytosis of macrophage. A: Absolute number of PEMs under the stimulation of 3% starch broth or murine hepatitis virus strain 3 (MHV-3) extracted from wild-type (WT) and fibrinogen-like protein 2 (Fgl2-/-) mice; B: MFI of FITC+ phagocyted E.Coli by PEMs from WT and Fgl2-/- mice at different time points; C: Expression of major histocompatibility complex II on WT and Fgl2-/- PEMs under the stimulation of 3% starch broth or MHV-3 infection. All data are presented as mean ± SD. These experiments were repeated at least three times. PEMs: Peritoneal exudate macrophages.