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©The Author(s) 2022.
World J Gastroenterol. Jan 28, 2022; 28(4): 464-478
Published online Jan 28, 2022. doi: 10.3748/wjg.v28.i4.464
Published online Jan 28, 2022. doi: 10.3748/wjg.v28.i4.464
Figure 5 Anti-migration and anti-invasion effects of DEAD-box helicase 51 knockdown was mediated by the AKT pathway.
A and B: AKT activator insulin-like growth factor 1 (IGF-1) reversed the anti-migration effect of DDX51 knockdown on the proliferation of TE-1 cells; C and D: AKT activator IGF-1 reversed the anti-invasion effect of DDX51 knockdown on the proliferation of TE-1 cells. aP < 0.05. All data were obtained from at least three independent experiments. Negative control was a scrambled small interfering RNA.
- Citation: Hu DX, Sun QF, Xu L, Lu HD, Zhang F, Li ZM, Zhang MY. Knockdown of DEAD-box 51 inhibits tumor growth of esophageal squamous cell carcinoma via the PI3K/AKT pathway. World J Gastroenterol 2022; 28(4): 464-478
- URL: https://www.wjgnet.com/1007-9327/full/v28/i4/464.htm
- DOI: https://dx.doi.org/10.3748/wjg.v28.i4.464