Knockdown of DEAD-box 51 inhibits tumor growth of esophageal squamous cell carcinoma via the PI3K/AKT pathway

Figure 2 Anti-proliferation effects of DEAD-box helicase 51 in esophageal cancer. Negative control (NC) small interfering RNA (siRNA) and DEAD-box helicase 51 (DDX51) siRNA were synthesized and transfected into Eca109 and TE-1 cells. A and B: Quantitative PCR assay was used for the detection of knockdown efficiencies; C: Western blot analysis of DDX51 expression in DDX51 siRNA-expressing cells; D and E: The effects of DDX51 on the viability of esophageal squamous cell carcinoma cells. ^aP < 0.05. All data were obtained from at least three independent experiments. NC was a scrambled siRNA.