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World J Gastroenterol. Jan 28, 2022; 28(4): 449-463
Published online Jan 28, 2022. doi: 10.3748/wjg.v28.i4.449
Figure 1
Figure 1 Schematic representation of DNA methylation and histone modifications. Histone modifications are many and determine a different chromatin status, modifying DNA accessibility and interfering with gene transcription. Methylation can also happen directly on the DNA sequence, mainly resulting in gene silencing. The image is original and was created with the use of Servier Medical Art modified templates, licensed under a Creative Common Attribution 3.0 Unported License (https://smart.servier.com). DNMT: DNA methyltransferase.