Serum metabolic profiling of targeted bile acids reveals potentially novel biomarkers for primary biliary cholangitis and autoimmune hepatitis

Table 6 Area under the curve, sensitivity and specificity of difference bile acids, conventional biochemical indicators in primary biliary cirrhosis, autoimmune hepatitis and control group

	AUC	Sensitivity	Specificity
LCA	0.68	0.82	0.50
LCA + TLCA	0.73	0.74	0.46
CDCA	0.74	0.74	0.54
AST	0.54	0.67	0.58
ALT	0.61	0.64	0.61
ALP	0.41	0.56	0.35
GGT	0.43	0.50	0.46
TBiL	0.53	0.59	0.42
DBiL	0.47	0.44	0.62
TBA	0.52	0.52	0.42

CDCA: Chenodeoxycholic acid; LCA: Lithocholic acid; TLCA: Taurolithocholic acid; ALT: Alanine transaminase; AST: Aspartate transaminase; GGT: Gamma glutamyl transpeptidase; ALP: Alkaline phosphatase; TBiL: Total bilirubin; DBiL: Direct bilirubin; TBA: Total bile acid; AUC: Area under the curve.