Hypoxia inducible factor 1α promotes interleukin-1 receptor antagonist expression during hepatic ischemia-reperfusion injury

Figure 1 Construction of a mouse model of hepatic ischemia-reperfusion injury and gene enrichment analysis. A: Model of ischemia-reperfusion injury (IRI) in mice; B: GO enrichment analysis upon IR for 3 h; C: Venn diagram shows that the expression of genes for IR 3 h and ischemia (IS) 1.5 h was more than 2-fold than that in the Sham group; D: Twenty-five genes were elevated in both IR 3 h and IS 1.5 h groups according to IS 1.5 h expression level. IS: Ischemia; IR: Ischemia-reperfusion; IRI: Ischemia-reperfusion injury.